Structural and functional features of central nervous system lymphatics

Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms Correspondence to: A.L. ([email protected]) or J.K. ([email protected]); Tel: 001 434-982-3858, Fax: 001 434-982-4380. All authors declare no financial interests or conflict of interests. Author Contributions A.L performed most of the experiments, analyzed the data, and contributed to experimental design and manuscript writing. I.S. performed all the surgeries and intracerebroventricular injections. T.K. assisted with the experiments and the analysis of the data. J.D.E, S.J.R. and J.D.P participated in the discussions and helped with the experimental design. N.C.D performed the xDCLN experiment. D.C. contributed to the imaging and the analysis of the electron microscopy images. J.W.M. contributed with data analysis of the human samples. K.S.L. contributed to experimental design and to manuscript editing. T.H.H. assisted to the intravital imaging experiment, contributed to experimental design and to manuscript editing. J.K. designed the study, assisted with data analysis, and wrote the manuscript. HHS Public Access Author manuscript Nature. Author manuscript; available in PMC 2016 January 16. Published in final edited form as: Nature. 2015 July 16; 523(7560): 337–341. doi:10.1038/nature14432. A uhor M anscript